Protective effects of alpha-lipoic acid on hair cell damage in diabetic zebrafish model

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WEB OF SCIENCE

5
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6

초록

Hearing impairment is one of the complications in diabetes mellitus; however, there are very few therapeutic studies on it. In this study, we investigated the protective effect of alpha-lipoic acid (ALA) on hearing loss in diabetic transgenic zebrafish and confirmed that ALA protects the loss of hair cells (HCs) caused by hyperglycemia. The data indicated that ALA has a protective effect on the damage to HCs in diabetic zebrafish.

키워드

Diabetes mellitusPancreatic beta-cellHair cellAlpha-lipoic acidZebrafishTARGETED ABLATIONPATHWAY
제목
Protective effects of alpha-lipoic acid on hair cell damage in diabetic zebrafish model
저자
Kim, EunmiLee, Dong-WonPark, Hae-ChulKim, Dong Hwee
DOI
10.1016/j.ymgmr.2021.100783
발행일
2021-09
유형
Article
저널명
Molecular Genetics and Metabolism Reports
28