Simultaneous patterning of proteins and cells through bioconjugation with photoreactable phospholipid polymers

초록

Photoreactable bioconjugated macromolecules were synthesized via atom transfer radical polymerization (ATRP), using an N-hydroxysuccinimide ester functional end group with the anti-biofouling 2-methacryloyloxyethyl phosphorylcholine (MPC) units and photoreactable 2-(4-azidobenzamido) ethyl methacrylate units. The polymer was then conjugated with bovine serum albumin (BSA), and the simultaneous patterning of BSA and L-929 fibroblast cells was prepared by a simple coating and irradiation (254 nm UV) process.

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