상세 보기
SIWV tetrapeptide and ROS-responsive prodrug conjugate for advanced glioblastoma therapy
- Park, Yoon Kyung;
- Jangili, Paramesh;
- Zi, Soyu;
- Kang, Rae Hyung;
- Kim, Dokyoung;
- ... Kim, Jong Seung
Citations
WEB OF SCIENCE
4Citations
SCOPUS
4초록
A new conjugate formulation, SIWV-PB-SN, based on glioblastoma (GBM)-homing SIWV tetrapeptide and an ROS-responsive prodrug is reported. SIWV-PB-SN selectively penetrates the GBM cells and releases anti-GBM drug (SN-38) via ROS-induced linker cleavage. This study presents a new insight for a more advanced therapeutic approach to overcoming GBM.
- 제목
- SIWV tetrapeptide and ROS-responsive prodrug conjugate for advanced glioblastoma therapy
- 저자
- Park, Yoon Kyung; Jangili, Paramesh; Zi, Soyu; Kang, Rae Hyung; Kim, Dokyoung; Kim, Jong Seung
- 발행일
- 2022-09-29
- 유형
- Article
- 권
- 58
- 호
- 78
- 페이지
- 10941 ~ 10944
- 언어
- ENG
- 출판사
- ROYAL SOC CHEMISTRY
- 발행국가
- 영국
- 분량
- 4 페이지
- ISSN
- E 1364-548X
P 1359-7345