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Gold-layered calcium phosphate plasmonic resonants for localized photothermal treatment of human epithelial cancer
- Kang, Jinyoung;
- Yang, Jaemoon;
- Lee, Jaewon;
- Oh, Seung Jae;
- Moon, Seyoung;
- ... Lee, Kwangyeol;
- 외 7명
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11Citations
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11초록
We fabricated de novo biocompatible mineral plasmon resonants for localized and systemic treatment of cancer. Biodegradable calcium-phosphate gold nanocomposites were synthesized for inducing a superior surface plasmon resonance effect. The combination of therapeutic antibody, Erbitux (R) and NIR laser with nanocomposites demonstrated the potential for selective bimodal cancer treatment by combination of EGFR-induced signaling inhibition as a systemic treatment and localized photothermal effects caused by the NIR laser.
키워드
THERAPY; NANOSHELLS; NANORODS; NANOCOMPOSITES; NANOCAGES; CELLS
- 제목
- Gold-layered calcium phosphate plasmonic resonants for localized photothermal treatment of human epithelial cancer
- 저자
- Kang, Jinyoung; Yang, Jaemoon; Lee, Jaewon; Oh, Seung Jae; Moon, Seyoung; Lee, Hong Jae; Lee, Sang Cheon; Son, Joo-Hiuk; Kim, Donghyun; Lee, Kwangyeol; Suh, Jin-Suck; Huh, Yong-Min; Haam, Seungjoo
- DOI
- 10.1039/b822835c
- 발행일
- 2009
- 유형
- Article
- 권
- 19
- 호
- 19
- 페이지
- 2902 ~ 2905