Micropore device for identification of 4-bit hydrogel barcode

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초록

We report the precise decoding of a shape-modulated hydrogel barcode particle using a micropore fluidic device. Using an electrical simulation, we deduced the optimal pore geometry that yields the maximal sensing signal. We fabricated hydrogel particles with different dimensions and prepared the micropore device along with a fluidic cell and a patch clamp. Accordingly, we experimentally determined the most appropriate shape of the hydrogel barcode particle that allows efficient differentiation between a 0 code and a 1 code. Thus, we successfully decoded 4-bit hydrogel barcode particles with high speed and high accuracy.

키워드

Low-aspect-ratio micropore sensor; Hydrogel barcode particle; Multiplexed detection; MICROPARTICLES; FABRICATION; MICRORNAS; ASSAY; DNA
제목
Micropore device for identification of 4-bit hydrogel barcode
저자
Ryu, Jihun; Kim, Hyeon Ung; Song, Chang-Woo; Shin, Sehyun; Bong, Ki Wan; Han, Chang-Soo
DOI
10.1016/j.snb.2019.127622
발행일
2020-03-15
유형
Article
저널명
Sensors and Actuators, B: Chemical
권
307