Fluorescence Probes for Tyrosine Dephosphorylation Based on Coumarin-Proline Conjugates

Choi, Kihang; Park, Bongjeong; Han, So-Yeong; Ahn, Hee Choon

doi:10.1246/cl.2011.290

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Fluorescence Probes for Tyrosine Dephosphorylation Based on Coumarin-Proline Conjugates

Choi, Kihang;
Park, Bongjeong;
Han, So-Yeong;
Ahn, Hee Choon

Citations

WEB OF SCIENCE

4

Citations

SCOPUS

5

초록

Proline-substituted coumarin compounds were prepared and used as environment-sensitive fluorescence probes. Phosphorylation and dephosphorylation of tyrosine derivatives labeled with the coumarin proline conjugate induced marked changes in fluorescence intensity allowing phosphatase activity to be monitored.

키워드

PHOSPHATASES; ACCEPTOR; SENSORS; PROTEIN-KINASE ACTIVITY; PHOSPHORYLATION

제목: Fluorescence Probes for Tyrosine Dephosphorylation Based on Coumarin-Proline Conjugates

저자: Choi, Kihang; Park, Bongjeong; Han, So-Yeong; Ahn, Hee Choon

DOI: 10.1246/cl.2011.290

발행일: 2011-03-05

유형: Article

저널명: Chemistry Letters

권: 40

호: 3

페이지: 290 ~ 291