Utility of tantalum (Ta) coating to improve surface hardness in vitro bioactivity and biocompatibility of Co-Cr

  • Vuong-Hung Pham; 
  • Lee, Seung-Hee; 
  • Li, Yuanlong; 
  • Kim, Hyoun-Ee; 
  • Shin, Kwan-Ha; 
  • ... Koh, Young-Hag
Citations

WEB OF SCIENCE

38
Citations

SCOPUS

48

초록

This study reports the utility of tantalum (Ta) coating for improving the surface hardness, in vitro bioactivity and biocompatibility of Co-Cr implants. The use of direct current sputtering allowed for the deposition of a dense and uniform Ta film onto a Co-Cr substrate, which was composed of beta-phase Ta grains. This hard Ta coating significantly improved the surface hardness of the Co-Cr by a factor of > 2.3. In addition, the Ta-deposited Co-Cr substrate showed a vigorous precipitation of apatite crystals on its surface after 4 weeks of immersion in simulated body fluid, suggesting its excellent in vitro bioactivity. This bioactive Ta coating led to a considerable improvement in the in vitro biocompatibility of the Co-Cr, which was assessed in terms of the attachment, proliferation and differentiation of pre-osteoblasts (MC3T3-E1). (C) 2013 Elsevier B.V. All rights reserved.

키워드

Biomaterials; Sputtering; Tantalum; Co-Cr substrates; Cytoskeleton; Differentiation; NEGATIVE SUBSTRATE BIAS; POROUS TANTALUM; TITANIUM; METAL; MECHANISM
제목
Utility of tantalum (Ta) coating to improve surface hardness in vitro bioactivity and biocompatibility of Co-Cr
저자
Vuong-Hung Pham; Lee, Seung-Hee; Li, Yuanlong; Kim, Hyoun-Ee; Shin, Kwan-Ha; Koh, Young-Hag
DOI
10.1016/j.tsf.2013.03.042
발행일
2013-06-01
유형
Article
저널명
Thin Solid Films
권
536
페이지
269 ~ 274