Photosensitizer and vancomycin-conjugated novel multifunctional magnetic particles as photoinactivation agents for selective killing of pathogenic bacteria

Choi, Kyong-Hoon; Lee, Hye-Jin; Park, Bong Joo; Wang, Kang-Kyun; Shin, Eon Pil; Park, Jong-Chul; Kim, Young Keun; Oh, Min-Kyu; Kim, Yong-Rok

doi:10.1039/c2cc17766h

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Photosensitizer and vancomycin-conjugated novel multifunctional magnetic particles as photoinactivation agents for selective killing of pathogenic bacteria

Choi, Kyong-Hoon;
Lee, Hye-Jin;
Park, Bong Joo;
Wang, Kang-Kyun;
Shin, Eon Pil;
... Kim, Young Keun;
... Oh, Min-Kyu;
외 2명

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81

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85

초록

Novel multifunctional magnetic particles (MMPs) conjugated with photosensitizer and vancomycin were fabricated by surface modification of Fe3O4 particles. The capacities to target, capture and inactivate pathogenic bacteria and good biocompatibility suggest that the MMPs have great potentials as photodynamic inactivation agents for serious bacterial contamination.

키워드

GRAM-NEGATIVE BACTERIA; PHOTODYNAMIC INACTIVATION; PHOTOTHERMAL AGENTS; POSITIVE BACTERIA; SINGLET OXYGEN; NANOPARTICLES; THERAPY

제목: Photosensitizer and vancomycin-conjugated novel multifunctional magnetic particles as photoinactivation agents for selective killing of pathogenic bacteria

저자: Choi, Kyong-Hoon; Lee, Hye-Jin; Park, Bong Joo; Wang, Kang-Kyun; Shin, Eon Pil; Park, Jong-Chul; Kim, Young Keun; Oh, Min-Kyu; Kim, Yong-Rok

DOI: 10.1039/c2cc17766h

발행일: 2012

유형: Article

저널명: Chemical Communications

권: 48

호: 38

페이지: 4591 ~ 4593