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초록
We report two-photon probes (FMg1 and FMg2) that can selectively detect intracellular free Mg2+ ([Mg2+](i)) in live cells and tissues by two-photon microscopy. Combined with BCaM, a two-photon probe for near-membrane Ca2+ ([Ca2+](m)), FMg2 allows dual-color imaging of Mg2+/Ca2+ activities in live cells and [Mg2+](i)/[Ca2+](m) distributions in live tissues at a depth of 100-200 mu m.
키워드
INTRACELLULAR MAGNESIUM; BINDING
- 제목
- Dual-Color Imaging of Magnesium/Calcium Ion Activities with Two-Photon Fluorescent Probes
- 저자
- Dong, Xiaohu; Han, Ji Hee; Heo, Cheol Ho; Kim, Hwan Myung; Liu, Zhihong; Cho, Bong Rae
- 발행일
- 2012-10-02
- 유형
- Article
- 권
- 84
- 호
- 19
- 페이지
- 8110 ~ 8113