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Bioactive triterpenoids from Callistemon lanceolatus
- Jeong, Wonsik;
- Hong, Seong Su;
- Kim, Nahyun;
- Yang, Young Taek;
- Shin, Yu Su;
- ... Lee, Dongho;
- 외 2명
Citations
WEB OF SCIENCE
31Citations
SCOPUS
36초록
A new triterpenoid, 30-hydroxyalphitolic acid 1, and eight known triterpenoids, alphitolic acid 2, lupenol 3, 3-acetoxy-olean-18-en-28-oic acid 4, betulinic acid 5, ursolic acid 6, betulinic acid 3-O-caffeate 7, morolic acid 3-O-caffeate 8, and ursolic acid 3-O-caffeate 9, were isolated from Callistemon lanceolatus. Their structures were determined using spectroscopic techniques, which included 1D- and 2D-NMR. All compounds were evaluated for the inhibition of LPS-induced nitric oxide production in murine macrophage RAW264.7 cells. Betulinic acid 3-O-caffeate 7 showed a moderate inhibitory effect on nitric oxide production with IC50 value of 15.4 mu M.
키워드
Callistemon lanceolatus; Myrtaceae; Triterpenoids; Betulinic acid 3-O-caffeate; NO production inhibitor; NITRIC-OXIDE; LEAVES; CONSTITUENTS; DERIVATIVES; CELLS; ACID; H-1
- 제목
- Bioactive triterpenoids from Callistemon lanceolatus
- 저자
- Jeong, Wonsik; Hong, Seong Su; Kim, Nahyun; Yang, Young Taek; Shin, Yu Su; Lee, Chul; Hwang, Bang Yeon; Lee, Dongho
- 발행일
- 2009-06
- 유형
- Article
- 권
- 32
- 호
- 6
- 페이지
- 845 ~ 849
- 언어
- ENG
- 출판사
- PHARMACEUTICAL SOC KOREA
- 발행국가
- 대한민국
- 분량
- 5 페이지
- ISSN
- E 1976-3786
P 0253-6269