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Inhibitory effect on NO production of phenolic compounds from Myristica fragrans
- Cuong, To Dao;
- Hung, Tran Manh;
- Na, MinKyun;
- Do Thi Ha;
- Kim, Jin Cheol;
- ... Lee, Dongho;
- 외 4명
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41초록
Three new phenolics: ((7S)-8'-(benzo[3',4']dioxol-1'-yl)-7-hydroxypropyl)benzene-2,4-diol (1), ((7S)-8'- (4'-hydroxy-3'-methoxyphenyl)-7-hydroxypropyl)benzene-2,4-diol (2) and ((8R,8'S)-7-(4-hydroxy-3-methoxyphenyl)-8'-methylbutan-8-yl)-3'-methoxybenzene-4',5'-diol (3), along with four known compounds (4-7) were isolated from the seeds of Myristica fragrans. Their chemical structures were established mainly by 1D and 2D NMR techniques and mass spectrometry. Their anti-inflammatory activity was evaluated against LPS-induced NO production in macrophage RAW264.7 cells. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.
키워드
Myristica fragrans; Myristicaceae; Phenolic; Anti-inflammatory activity; LIGNANS; IDENTIFICATION; CONSTITUENTS; MACE; OIL
- 제목
- Inhibitory effect on NO production of phenolic compounds from Myristica fragrans
- 저자
- Cuong, To Dao; Hung, Tran Manh; Na, MinKyun; Do Thi Ha; Kim, Jin Cheol; Lee, Dongho; Ryoo, SungWoo; Lee, Jeong Hyung; Choi, Jae Sue; Min, Byung Sun
- 발행일
- 2011-11-15
- 유형
- Article
- 권
- 21
- 호
- 22
- 페이지
- 6884 ~ 6887
- 언어
- ENG
- 출판사
- PERGAMON-ELSEVIER SCIENCE LTD
- 발행국가
- 영국
- 분량
- 4 페이지
- ISSN
- E 1464-3405
P 0960-894X