In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Koo, Heebeom; Lee, Hyejung; Lee, Sojin; Min, Kyung Hyun; Kim, Min Sang; Lee, Doo Sung; Choi, Yongseok; Kwon, Ick Chan; Kim, Kwangmeyung; Jeong, Seo Young

doi:10.1039/c0cc01413c

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In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Koo, Heebeom;
Lee, Hyejung;
Lee, Sojin;
Min, Kyung Hyun;
Kim, Min Sang;
... Choi, Yongseok;
외 4명

Citations

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168

Citations

SCOPUS

187

초록

We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

키워드

BLOCK-COPOLYMER MICELLES; CANCER-THERAPY; SINGLET OXYGEN; NANOPARTICLES; DELIVERY; PHOTOSENSITIZER; GENERATION; LIPOSOMES; APOPTOSIS; EFFICACY

제목: In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

저자: Koo, Heebeom; Lee, Hyejung; Lee, Sojin; Min, Kyung Hyun; Kim, Min Sang; Lee, Doo Sung; Choi, Yongseok; Kwon, Ick Chan; Kim, Kwangmeyung; Jeong, Seo Young

DOI: 10.1039/c0cc01413c

발행일: 2010

유형: Article

저널명: Chemical Communications

권: 46

호: 31

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