In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

  • Koo, Heebeom; 
  • Lee, Hyejung; 
  • Lee, Sojin; 
  • Min, Kyung Hyun; 
  • Kim, Min Sang; 
  • ... Choi, Yongseok; 
  • 외 4명
Citations

WEB OF SCIENCE

168
Citations

SCOPUS

187

초록

We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

키워드

BLOCK-COPOLYMER MICELLES; CANCER-THERAPY; SINGLET OXYGEN; NANOPARTICLES; DELIVERY; PHOTOSENSITIZER; GENERATION; LIPOSOMES; APOPTOSIS; EFFICACY
제목
In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles
저자
Koo, Heebeom; Lee, Hyejung; Lee, Sojin; Min, Kyung Hyun; Kim, Min Sang; Lee, Doo Sung; Choi, Yongseok; Kwon, Ick Chan; Kim, Kwangmeyung; Jeong, Seo Young
DOI
10.1039/c0cc01413c
발행일
2010
유형
Article
저널명
Chemical Communications
권
46
호
31
페이지
5668 ~ 5670