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A protecting group-free divergent synthesis of natural benzofurans via one-pot synthesis of 2-bromo-6-hydroxybenzofurans
- Sivaraman, Aneesh;
- Harmalkar, Dipesh S.;
- Kang, Jiyoon;
- Choi, Yongseok;
- Lee, Kyeong
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WEB OF SCIENCE
15Citations
SCOPUS
16초록
2-Bromo-6-hydroxybenzofurans are potentially versatile intermediates for the divergent synthesis of numerous benzofuran-based natural products and their analogues. Herein we report the first one-pot strategy for the efficient synthesis of 2-bromo-6-hydroxybenzofurans. The present protocol provides shorter routes for the synthesis of moracins M, N, O and P; gramniphenols F and G; and morunigrol C using a protecting group-free approach.
키워드
EFFICIENT TOTAL-SYNTHESIS; 1ST TOTAL-SYNTHESIS; INTRAMOLECULAR CYCLIZATION; MORACIN O; CICERFURAN; 2-ARYLBENZOFURANS; INHIBITORS; PHYTOALEXIN; DERIVATIVES; CONVENIENT
- 제목
- A protecting group-free divergent synthesis of natural benzofurans via one-pot synthesis of 2-bromo-6-hydroxybenzofurans
- 저자
- Sivaraman, Aneesh; Harmalkar, Dipesh S.; Kang, Jiyoon; Choi, Yongseok; Lee, Kyeong
- 발행일
- 2019-02-28
- 유형
- Article
- 권
- 17
- 호
- 8
- 페이지
- 2153 ~ 2161