Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities

  • Singh, Sarbjit; 
  • Bhattarai, Deepak; 
  • Veeraswamy, Gajulapati; 
  • Choi, Yongseok; 
  • Lee, Kyeong
Citations

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10
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초록

In the recent few years, the emergence of nucleosides containing modified sugar ring or modified base moiety has gained much attention due to their enhanced biological activities as compared to parent nucleosides containing 5-carbon ribose or deoxyribose sugar ring. In this review, we highlight the recent advances in synthesis and biological activities of nucleosides containing modified sugar rings reported between years 2010 to 2015.

키워드

Functionalized nucleosides; modified nucleosides; fluorinated nucleosides; selenonucleosides; thionucleosides; biologically active nucleosides; POTENT ANTIVIRAL AGENTS; S-ADENOSYLHOMOCYSTEINE HYDROLASE; PHOSPHONIC ACID NUCLEOSIDES; 3,4-DIMETHOXYBENZYL PROTECTING GROUPS; L-CYCLOPENTENONE DERIVATIVES; A(3) ADENOSINE RECEPTOR; HERPES-SIMPLEX-VIRUS; ANTI-HIV ACTIVITY; CARBOCYCLIC 2'-OXA-3'-AZANUCLEOSIDES; PYRIMIDINE PYRANONUCLEOSIDES
제목
Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities
저자
Singh, Sarbjit; Bhattarai, Deepak; Veeraswamy, Gajulapati; Choi, Yongseok; Lee, Kyeong
DOI
10.2174/1385272819666150803235458
발행일
2016
유형
Article
저널명
Current Organic Chemistry
권
20
호
8
페이지
856 ~ 897