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Porous TiO2 films on Ti implants for controlled release of tetracycline-hydrochloride (TCH)
- Han, Cheol-Min;
- Lee, Eun-Jung;
- Kim, Hyoun-Ee;
- Koh, Young-Hag;
- Jang, Jun-Hyeog
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23초록
Micro- and nano-porous TiO2 films were created on the surface of Ti implants using micro-arc oxidation and anodic titanium oxide treatments, respectively, to load a sol-gel derived silica xerogel for the controlled release of the antibiotic drug, tetracycline-hydrochloride (TCH). When the silica xerogel containing TCH was loaded into porous TiO2 films, a very high drug loading efficiency was observed compared to when it was loaded in Ti implants without a TiO2 film. Moreover, TCH was released in a controlled manner for up to 7 days. (C) 2011 Elsevier B.V. All rights reserved.
키워드
Micro-arc oxidation; Anodic titanium oxide; Silica xerogel; Controlled drug release; STAPHYLOCOCCUS-AUREUS; SILICA XEROGEL; SOL-GEL; TITANIUM; BONE; SUSCEPTIBILITY; ADHESION; HYBRID
- 제목
- Porous TiO2 films on Ti implants for controlled release of tetracycline-hydrochloride (TCH)
- 저자
- Han, Cheol-Min; Lee, Eun-Jung; Kim, Hyoun-Ee; Koh, Young-Hag; Jang, Jun-Hyeog
- 발행일
- 2011-09-01
- 유형
- Article
- 저널명
- Thin Solid Films
- 권
- 519
- 호
- 22
- 페이지
- 8074 ~ 8076