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파래 추출물의 항응고 활성과 항암 활성에 관한 연구
- 임은정;
- 임은정;
- 김지영;
- 이유현;
- 효진녕;
- ... 김영준;
- 외 1명
초록
The study was performed to investigate the biological activity of Enteromorpha intestinalis. In order to examine its blood anti-coagulant effects, Enteromorpha intestinalis was extracted with cold water, methanol, hot water, HCl and NaOH. In general, the alkali extract of Enteromorpha intestinalis was approximately 17 times stronger than the control. The anti-cancer effects of select extracts(methanol, hot water, 0.1 N NaOH, 1 N NaOH) were determined in human melanoma cells(B16/ F10), fibrosarcoma cells(HT1080) and breast cancer cells(MCF7) by MTT assay. With the treatment of 250 ㎍/㎖ of methanol extracts. HT1080, B16/F10 and MCF7 cell viabilities significantly decreased to 8.06%, 3.62% and 10.10%, respectively. Thus these results strongly support the possibie use of Enteromorpha intestinalis as a functional materials.
키워드
- 제목
- 파래 추출물의 항응고 활성과 항암 활성에 관한 연구
- 제목 (타언어)
- The Anticoagulant and Anticancer Activities of Enteromorpha intestinalis Extracts
- 저자
- 임은정; 임은정; 김지영; 이유현; 효진녕; 김영준; 조홍연
- 발행일
- 2008
- 저널명
- 한국식품영양학회지
- 권
- 21
- 호
- 1
- 페이지
- 7 ~ 14