Pyrophosphate-Selective Fluorescent Chemosensor Based on 1, 8-Naphthalimide-DPA-Zn(II) Complex and Its Application for Cell Imaging

  • Zhang, Jun Feng
  • Kim, Sooyeon
  • Han, Ji Hae
  • Lee, Seung-Jea
  • Pradhan, Tuhin
  • ... Kim, Jong Seung
  • 외 3명
Citations

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167

초록

A new zinc(II) complex with a two-dipicolylamine-substituted 1,8-naphthalimide for recognition of pyrophosphate with ratiometrical fluorescence changes in aqueous solution has been synthesized and characterized. Its biological application to monitor the intracellular pyrophosphate (PPi) was successfully demonstrated by the observation that the fluorescence of 1 was enhanced by the presence of the Zn(2+) ion and was quenched by addition of PPi.

키워드

CONJUGATED POLYELECTROLYTESENSORRECOGNITIONEXCIMERSYSTEMWATERASSAY
제목
Pyrophosphate-Selective Fluorescent Chemosensor Based on 1, 8-Naphthalimide-DPA-Zn(II) Complex and Its Application for Cell Imaging
저자
Zhang, Jun FengKim, SooyeonHan, Ji HaeLee, Seung-JeaPradhan, TuhinCao, Qian YongLee, Suk JoongKang, ChulhunKim, Jong Seung
DOI
10.1021/ol202159x
발행일
2011-10-07
유형
Article
저널명
Organic Letters
13
19
페이지
5294 ~ 5297