Fabrication and characterisation of CMOS compatible silicon nanowire biosensor

  • Kang, G. B.
  • Park, J. M.
  • Kim, S. G.
  • Koo, J. G.
  • Park, J. H.
  • 외 2명
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초록

A silicon nanowire (SiNW) biosensor for label-free and real-time detection has been fabricated by complementary metal-oxide semiconductor (CMOS) technology. For the detection of prostate-specific antigen (PSA) used as a biomarker of prostate cancer the SiNW surface was modified to immobilise the antibody of PSA (anti-PSA). Real-time monitoring reveals the change in conductivity of the SiNW on specific binding of PSA to anti-PSA. For 355 nm SiNW, the response to 10 ng/ml of PSA was 7.3%.

키워드

DNA
제목
Fabrication and characterisation of CMOS compatible silicon nanowire biosensor
저자
Kang, G. B.Park, J. M.Kim, S. G.Koo, J. G.Park, J. H.Sohn, Y. -S.Kim, Y. T.
DOI
10.1049/el:20081876
발행일
2008-07-31
유형
Article
저널명
Electronics Letters
44
16
페이지
953 ~ 955