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초록
A silicon nanowire (SiNW) biosensor for label-free and real-time detection has been fabricated by complementary metal-oxide semiconductor (CMOS) technology. For the detection of prostate-specific antigen (PSA) used as a biomarker of prostate cancer the SiNW surface was modified to immobilise the antibody of PSA (anti-PSA). Real-time monitoring reveals the change in conductivity of the SiNW on specific binding of PSA to anti-PSA. For 355 nm SiNW, the response to 10 ng/ml of PSA was 7.3%.
키워드
DNA
- 제목
- Fabrication and characterisation of CMOS compatible silicon nanowire biosensor
- 저자
- Kang, G. B.; Park, J. M.; Kim, S. G.; Koo, J. G.; Park, J. H.; Sohn, Y. -S.; Kim, Y. T.
- 발행일
- 2008-07-31
- 유형
- Article
- 권
- 44
- 호
- 16
- 페이지
- 953 ~ 955