Prevalence of osteoarthritis in Korean patients with chronic obstructive pulmonary disease: a cross-sectional study

초록

Objective: Chronic obstructive pulmonary disease (COPD) is an inflammatory disease associated with physical disability and various comorbidities. The disease often leads to musculoskeletal weakness and may be associated with the prevalence of osteoarthritis (OA). Here, we aimed to investigate the prevalence of OA among patients with COPD and the relationship between COPD and OA. Design: Cross-sectional study Setting: Nationwide Subjects: Participants (4324 men and 5499 women) who underwent pulmonary function tests, knee and hip radiography, and health surveys. Intervention: Comparison of the prevalence of OA between patients with and without COPD, adjusted for age, body mass index, smoking status, hypertension, diabetes mellitus, dyslipidemia and occupation. Main outcome measures: The odds ratios (ORs) and 95% confidence intervals (CIs) were used to determine the prevalence of OA in patients with COPD. Results: The overall prevalence of COPD in Korea was 1.6% (3.6% men; 0.1% women). The prevalence of OA among male patients with COPD was 11%, which is higher than that among those without COPD (6.6%). However, a significant difference in OA prevalence was not found between the COPD and non-COPD groups (OR: 1.50; 95% CI: 0.87-2.57). Conclusion: The prevalence of OA was higher among males with COPD than among those without COPD; however, no significant relationship was found between the presence of COPD and the prevalence of OA.

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