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Innovative approach of nanopore-based metagenomic sequencing for rapid identification of bacterial pathogens in joint fluid: A pilot study
- Sung, Yoon Hyun;
- Jeong, Woong Kyo;
- Lee, Hak Jun;
- Suh, Jin Woong;
- Kim, Jeong Yeon;
- ... Yoon, Young Kyung
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0초록
Analysis of 11 clinical samples of joint fluid in this pilot study demonstrated proof-of-concept for nanopore-based metagenomic sequencing to serve as a complementary real-time diagnostic technique for septic arthritis, with a sensitivity of 75.0 % and specificity of 57.1 %, compared to the gold standard method of bacterial culture.
키워드
Synovial fluid; Nanopore sequencing; Infectious arthritis; Point-of-care testing
- 제목
- Innovative approach of nanopore-based metagenomic sequencing for rapid identification of bacterial pathogens in joint fluid: A pilot study
- 저자
- Sung, Yoon Hyun; Jeong, Woong Kyo; Lee, Hak Jun; Suh, Jin Woong; Kim, Jeong Yeon; Yoon, Young Kyung
- 발행일
- 2024-12
- 유형
- Article
- 권
- 110
- 호
- 4