Immobilization-free screening of aptamers assisted by graphene oxide

  • Park, Jee-Woong
  • Tatavarty, Rameshwar
  • Kim, Dae Woo
  • Jung, Hee-Tae
  • Gu, Man Bock
Citations

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초록

Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

키워드

IN-VITRO SELECTIONPLATFORMTHROMBINLIGANDSASSAY
제목
Immobilization-free screening of aptamers assisted by graphene oxide
저자
Park, Jee-WoongTatavarty, RameshwarKim, Dae WooJung, Hee-TaeGu, Man Bock
DOI
10.1039/c2cc16473f
발행일
2012
유형
Article
저널명
Chemical Communications
48
15
페이지
2071 ~ 2073