Switching Regioselectivity in Crossed Acyloin Condensations between Aromatic Aldehydes and Acetaldehyde by Altering N-Heterocyclic Carbene Catalysts

Jin, Ming Yu; Kim, Sun Min; Han, Hogyu; Ryu, Do Hyun; Yang, Jung Woon

doi:10.1021/ol102937w

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Switching Regioselectivity in Crossed Acyloin Condensations between Aromatic Aldehydes and Acetaldehyde by Altering N-Heterocyclic Carbene Catalysts

Jin, Ming Yu;
Kim, Sun Min;
Han, Hogyu;
Ryu, Do Hyun;
Yang, Jung Woon

Citations

WEB OF SCIENCE

77

Citations

SCOPUS

85

초록

An unprecedented high level of regioselectivities (up to 96%) in the intermolecular crossed acyloin condensations of various aromatic aldehydes with acetaldehyde was realized by an appropriate choice of N-heterocyclic carbene catalysts.

키워드

KETONE BENZOIN REACTIONS; YEAST PYRUVATE DECARBOXYLASE; MANNICH REACTIONS; ALDOL REACTION; MECHANISM; ORGANOCATALYSIS; DIARYLPROLINOL

제목: Switching Regioselectivity in Crossed Acyloin Condensations between Aromatic Aldehydes and Acetaldehyde by Altering N-Heterocyclic Carbene Catalysts

저자: Jin, Ming Yu; Kim, Sun Min; Han, Hogyu; Ryu, Do Hyun; Yang, Jung Woon

DOI: 10.1021/ol102937w

발행일: 2011-03-04

유형: Article

저널명: Organic Letters

권: 13

호: 5

페이지: 880 ~ 883