Prevention and management of non-steroidal anti-inflammatory drugs-induced small intestinal injury

  • Park, Sung Chul
  • Chun, Hoon Jai
  • Kang, Chang Don
  • Sul, Donggeun
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초록

Non-steroidal anti-inflammatory drug (NSAID)-induced small bowel injury is a topic that deserves attention since the advent of capsule endoscopy and balloon enteroscopy. NSAID enteropathy is common and is mostly asymptomatic. However, massive bleeding, stricture, or perforation may occur. The pathogenesis of small intestine injury by NSAIDs is complex and different from that of the upper gastrointestinal tract. No drug has yet been developed that can completely prevent or treat NSAID enteropathy. Therefore, a long-term randomized study in chronic NSAID users is needed. (C) 2011 Baishideng. All rights reserved.

키워드

Non-steroidal anti-inflammatory drugsSmall intestinal injuryPreventionTreatmentSMALL-BOWEL INJURYPLACEBO-CONTROLLED TRIALVIDEO CAPSULE ENDOSCOPYINDUCED ENTEROPATHYRHEUMATOID-ARTHRITISBOVINE COLOSTRUMBLOOD-LOSSGASTROINTESTINAL PERMEABILITYHEALTHY-VOLUNTEERSHYDROGEN-SULFIDE
제목
Prevention and management of non-steroidal anti-inflammatory drugs-induced small intestinal injury
저자
Park, Sung ChulChun, Hoon JaiKang, Chang DonSul, Donggeun
DOI
10.3748/wjg.v17.i42.4647
발행일
2011-11-14
유형
Article
저널명
World Journal of Gastroenterology
17
42
페이지
4647 ~ 4653