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초록
A new method for the preparation of 4-substituted 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides is described. Treatment of t-butyl N-phenylsulfamoylcarbamate derivatives (1) with different aldehydes afforded the corresponding intramolecular cyclized products 2 under trifluoroacetic acid conditions. (C) 2011 Wiley Periodicals, Inc. Heteroatom Chem 22: 192-197, 2011; View this article online at wileyonlinelibrary. com. DOI 10.1002/hc.20670
키워드
NEUTRON-CAPTURE THERAPY; CARBOSILANE COMPOUNDS; CYCLIC SULFAMIDES; BNCT
- 제목
- Facile Synthesis of 4-Substituted 3,4-Dihydro-1H-2,1,3-Benzothiadiazine 2,2-Dioxides
- 저자
- Lee, Chai-Ho; Jin, Guo Fan; Lim, Hyun Wha; Yang, Eun Hye; Lee, Jong-Dae; Nakamura, Hiroyuki; Ban, Hyun Seung; Kang, Sang Ook
- DOI
- 10.1002/hc.20670
- 발행일
- 2011
- 유형
- Article
- 권
- 22
- 호
- 2
- 페이지
- 192 ~ 197