Early onset depression has different characteristics from middle-aged depression in terms of circadian rhythm

초록

Objective: The aim of this study was to identify the unique biological and circadian rhythmic characteristics of patients with early-onset depression compared to patients with middle-age-onset depression. Methods: A total of 240 subjects were recruited in the study and divided into three groups: healthy young individuals, patients with early-onset depression, and middle-aged patients with unipolar depression. Patients then filled out questionnaires related to biological rhythm disturbances, mood symptoms, diurnal preference, and seasonality. Results: Patients with early-onset depression had significantly different clinical features in terms of mood disorders, diurnal preference, and biological rhythm disturbances compared to middle-aged patients with unipolar depression. Conclusion: Results of this study suggest that early-onset depression is different from middle-age-onset unipolar depression but similar to bipolar disorder. Copyright © 2020 Korean Academy of Sleep Medicine

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