상세 보기
초록
PG-F2 and PG-HMW from Panax ginseng are pectintype polysaccharides and PG-HMW might be an arabinogalactan. They demonstrated strong anti-adhesive activities against oral and skin pathogens to host cell lines in a dose-dependent manner from 0.1 to 2.0 mg/ml. While enzymatic hydrolysis caused complete loss of anti-adhesive activities, partial hydrolysis produced oligosaccharides with anti-adhesive properties. PG-F2 and PG-HMW might have a selective anti-adhesive effect against certain pathogenic bacteria without adverse effects on commensal bacteria.
키워드
polysaccharide; Panax ginseng; anti-adhesion; pathogenic bacteria; INTESTINAL EPITHELIAL-CELLS; ACIDIC POLYSACCHARIDE; PORPHYROMONAS-GINGIVALIS; STAPHYLOCOCCUS-AUREUS; ANTIADHESIVE ACTIVITY; BACTERIAL ADHESION; IN-VITRO; ADHERENCE; BINDING
- 제목
- Inhibition of Pathogen Adhesion to Host Cells by Polysaccharides from Panax ginseng
- 저자
- Lee, Ji-Hye; Shim, Jin Sun; Chung, Mi-Sook; Lim, Seung-Taik; Kim, Kyung Hyun
- 발행일
- 2009-01
- 유형
- Article
- 권
- 73
- 호
- 1
- 페이지
- 209 ~ 212