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pH-Triggered Drug-Releasing Magnetic Nanoparticles for Cancer Therapy Guided by Molecular Imaging by MRI
- Lim, Eun-Kyung;
- Huh, Yong-Min;
- Yang, Jaemoon;
- Lee, Kwangyeol;
- Suh, Jin-Suck;
- 외 1명
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222초록
pH-sensitive drug-delivering magnetic nanoparticles (DMNPs) have been developed as theragnostic nanocarriers that release doxorubicin (DOX) under acidic conditions within cancer cells. The drug release kinetics of the DMNPs, combined with the nanoparticle accumulation pattern in tumor cells, can be monitored by magnetic resonance imaging (MRI) to guide decisions regarding the optimization of drug dosing schedules.
키워드
drug delivery; magnetic resonance imaging; nanoparticles; theragnostics; BREAST-CANCER; IN-VIVO; BIOMEDICAL APPLICATIONS; CONTRAST AGENTS; FATTY ACID; DELIVERY; TUMOR; NANOCARRIERS; CHEMOTHERAPY; PLATFORM
- 제목
- pH-Triggered Drug-Releasing Magnetic Nanoparticles for Cancer Therapy Guided by Molecular Imaging by MRI
- 저자
- Lim, Eun-Kyung; Huh, Yong-Min; Yang, Jaemoon; Lee, Kwangyeol; Suh, Jin-Suck; Haam, Seungjoo
- 발행일
- 2011-06-03
- 유형
- Article
- 권
- 23
- 호
- 21
- 페이지
- 2436 ~ +