An amorphane sesquiterpene and a benzofuran glucoside from Eupatorium coelestinum

  • Dan Thi Thuy Hang; 
  • Tran Thi Hong Hanh; 
  • Chau Van Minh; 
  • Phan Van Kiem; 
  • Tran Huy Thai; 
  • ... Lee, Dongho; 
  • 외 1명
Citations

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SCOPUS

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초록

A phytochemical investigation of the aerial parts of Eupatorium coelestinum led to the isolation of an amorphane sesquiterpene and a benzofuran glucoside. By means of spectroscopic methods, their structures were determined as 5 alpha,8 alpha-epoxy-4 alpha,6 beta-dihydroxyamorphan-2-one (1) and 2R*,3S*-toxol-7-O-beta-D-glucopyranoside (2). Compounds 1 significantly inhibited NF-kappa B activity in TNF-alpha-stimulated HeLa cells with the IC50 of 12.4 mu M. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

키워드

Eupatorium coelestinum; Asteraceae; Amorphane sesquiterpene; Benzofuran; NF-kappa B; FLAVONES
제목
An amorphane sesquiterpene and a benzofuran glucoside from Eupatorium coelestinum
저자
Dan Thi Thuy Hang; Tran Thi Hong Hanh; Chau Van Minh; Phan Van Kiem; Tran Huy Thai; Lee, Dongho; Nguyen Tien Dat
DOI
10.1016/j.phytol.2011.08.004
발행일
2011-09
유형
Article
저널명
Phytochemistry Letters
권
4
호
3
페이지
377 ~ 379