An amorphane sesquiterpene and a benzofuran glucoside from Eupatorium coelestinum

Dan Thi Thuy Hang; Tran Thi Hong Hanh; Chau Van Minh; Phan Van Kiem; Tran Huy Thai; Lee, Dongho; Nguyen Tien Dat

doi:10.1016/j.phytol.2011.08.004

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An amorphane sesquiterpene and a benzofuran glucoside from Eupatorium coelestinum

Dan Thi Thuy Hang;
Tran Thi Hong Hanh;
Chau Van Minh;
Phan Van Kiem;
Tran Huy Thai;
... Lee, Dongho;
외 1명

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초록

A phytochemical investigation of the aerial parts of Eupatorium coelestinum led to the isolation of an amorphane sesquiterpene and a benzofuran glucoside. By means of spectroscopic methods, their structures were determined as 5 alpha,8 alpha-epoxy-4 alpha,6 beta-dihydroxyamorphan-2-one (1) and 2R*,3S*-toxol-7-O-beta-D-glucopyranoside (2). Compounds 1 significantly inhibited NF-kappa B activity in TNF-alpha-stimulated HeLa cells with the IC50 of 12.4 mu M. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

키워드

Eupatorium coelestinum; Asteraceae; Amorphane sesquiterpene; Benzofuran; NF-kappa B; FLAVONES

제목: An amorphane sesquiterpene and a benzofuran glucoside from Eupatorium coelestinum

저자: Dan Thi Thuy Hang; Tran Thi Hong Hanh; Chau Van Minh; Phan Van Kiem; Tran Huy Thai; Lee, Dongho; Nguyen Tien Dat

DOI: 10.1016/j.phytol.2011.08.004

발행일: 2011-09

유형: Article

저널명: Phytochemistry Letters

권: 4

호: 3

페이지: 377 ~ 379