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Selective enrichment of cysteine-containing peptides using SPDP-Functionalized superparamagnetic Fe3O4@SiO2 nanoparticles: Application to comprehensive proteomic profiling
- Palani, Arudra;
- Lee, Je-Sun;
- Huh, Jiyoung;
- Kim, Minsik;
- Lee, Yeon-Ji;
- ... Lee, Kwangyeol;
- ... Lee, Sang-Won;
- 외 1명
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39Citations
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42초록
Superparamagnetic Fe3O4@SiO2 core-shell nanoparticles (ca. 30 nm diameter), which are surface-modified with a thiol-specific functional group, exhibit superb capturing efficiency toward cysteinyl peptides without contamination from nonspecifically interacting peptides, as clearly evidenced through LC/MS/MS analysis.
키워드
superparamagnetic nanoparticle; surface modification; cysteine containing peptide enrichment; tandem mass spectrometry; proteomics; MASS-SPECTROMETRY; NANOCRYSTALS
- 제목
- Selective enrichment of cysteine-containing peptides using SPDP-Functionalized superparamagnetic Fe3O4@SiO2 nanoparticles: Application to comprehensive proteomic profiling
- 저자
- Palani, Arudra; Lee, Je-Sun; Huh, Jiyoung; Kim, Minsik; Lee, Yeon-Ji; Chang, Jeong Ho; Lee, Kwangyeol; Lee, Sang-Won
- 발행일
- 2008-08
- 유형
- Article
- 권
- 7
- 호
- 8
- 페이지
- 3591 ~ 3596
- 언어
- ENG
- 출판사
- AMER CHEMICAL SOC
- 발행국가
- 미국
- 분량
- 6 페이지
- ISSN
- E 1535-3907
P 1535-3893