Clinical features and prognostic relevance of ovarian involvement in non-Hodgkin's lymphoma: A Consortium for Improving Survival of Lymphoma (CISL) report

  • Yun, Jina
  • Kim, Seok Jin
  • Won, Jong Ho
  • Choi, Chul Won
  • Eom, Hyeon Seok
  • 외 5명
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초록

Fourteen patients had primary ovarian lymphoma, while eighteen patients had secondary ovarian involvement. There was no significant difference in survival rates between primary and secondary involvement with diffuse large B-cell lymphoma (DLBCL), the most common subtype. The 5-year overall survivals of primary and secondary involvement with DLBCL were 70.0% and 59.3%, respectively. The localized bilateral ovarian involvement showed poorer survival compared to stage III/IV patients with secondary ovarian involvement. Treatment outcomes of secondary ovarian involvement in non-Hodgkin's lymphoma were comparable to those of primary ovarian involvement, suggesting that ovarian involvement does not necessarily predict a worse prognosis for NHL patients. (C) 2010 Elsevier Ltd. All rights reserved.

키워드

LymphomaOvaryPrognosisRituximabChemotherapyB-cellT-cellFEMALE GENITAL-TRACTCHEMOTHERAPY
제목
Clinical features and prognostic relevance of ovarian involvement in non-Hodgkin's lymphoma: A Consortium for Improving Survival of Lymphoma (CISL) report
저자
Yun, JinaKim, Seok JinWon, Jong HoChoi, Chul WonEom, Hyeon SeokKim, Jin SeokKim, Min KyoungKwak, Jae-YongKim, Won SeogSuh, Cheolwon
DOI
10.1016/j.leukres.2010.02.010
발행일
2010-09
유형
Article
저널명
Leukemia Research
34
9
페이지
1175 ~ 1179