Phytochemicals for the treatment of COVID-19

Citations

WEB OF SCIENCE

18
Citations

SCOPUS

31

초록

The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle.

키워드

antiviralsalkaloidscoronavirusesCOVID-19flavonoidsphytochemicalsnatural productsSARS-CoV-2SARS-COV-2INHIBITPROTEASEANDROGRAPHOLIDEREPLICATIONEXTRACTTMPRSS2
제목
Phytochemicals for the treatment of COVID-19
저자
Espano, EricaKim, JiyeonLee, KihoKim, Jeong-Ki
DOI
10.1007/s12275-021-1467-z
발행일
2021-11
유형
Review
저널명
Journal of Microbiology
59
11
페이지
959 ~ 977