Highly selective two-photon imaging of cysteine in cancerous cells and tissues

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WEB OF SCIENCE

67
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SCOPUS

68

초록

Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.

키워드

COLORIMETRIC CHEMOSENSORS; FLUORESCENT-PROBE; RECENT PROGRESS; METAL-IONS; GLUTATHIONE; THIOLS; SENSOR; TRANSFERASES; HOMOCYSTEINE; BODIPY
제목
Highly selective two-photon imaging of cysteine in cancerous cells and tissues
저자
Lee, Yun Hak; Ren, Wen Xiu; Han, Jiyou; Sunwoo, Kyoung; Lim, Ja-Yun; Kim, Jong-Hoon; Kim, Jong Seung
DOI
10.1039/c5cc06038a
발행일
2015
유형
Article
저널명
Chemical Communications
권
51
호
76
페이지
14401 ~ 14404