Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold

  • Singh, Sarbjit; 
  • Goo, Jail; 
  • Gajulapati, Veeraswamy; 
  • Chang, Tong-Shin; 
  • Lee, Kyeong; 
  • ... Choi, Yongseok
Citations

WEB OF SCIENCE

16
Citations

SCOPUS

16

초록

In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.

키워드

Anticancer agents; azepane scaffold; chemotherapeutics; histone deacetylases; kinase inhibitors; tubulin inhibitors; phototherapeutic agents; hormone modulators; GERANYLGERANYLTRANSFERASE-I INHIBITORS; NUCLEOSOME CORE PARTICLE; STRUCTURE-BASED DESIGN; P-GLYCOPROTEIN; 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE; PROTEASOME INHIBITORS; BIOLOGICAL EVALUATION; DERIVATIVES BEARING; RECENT PROGRESS; CELL LINES
제목
Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold
저자
Singh, Sarbjit; Goo, Jail; Gajulapati, Veeraswamy; Chang, Tong-Shin; Lee, Kyeong; Choi, Yongseok
DOI
10.2174/1871520615666150916091750
발행일
2016
유형
Article
저널명
Anti-Cancer Agents in Medicinal Chemistry
권
16
호
5
페이지
539 ~ 557