Antimalarial activity of a new stilbene glycoside from Parthenocissus tricuspidata in mice

초록

A novel stilbene glycoside [piceid-(1 -> 6)-beta-D-glucopyranoside; PBG] from Parthenocissus tricuspidata was tested in vivo against Plasmodium berghei. PBG exhibited significant blood schizontocidal activity in a 4-day early infection, a repository evaluation, and an established infection, with a significant mean survival time comparable to that obtained with the standard drug, chloroquine (5 mg . kg(-1) . day(-1)).

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