Surface-Treatment-Induced Three-Dimensional Capillary Morphogenesis in a Microfluidic Platform

Chung, Seok; Sudo, Ryo; Zervantonakis, Ioannis K.; Rimchala, Tharathorn; Kamm, Roger D.

doi:10.1002/adma.200901727

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Surface-Treatment-Induced Three-Dimensional Capillary Morphogenesis in a Microfluidic Platform

Chung, Seok;
Sudo, Ryo;
Zervantonakis, Ioannis K.;
Rimchala, Tharathorn;
Kamm, Roger D.

Citations

WEB OF SCIENCE

75

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SCOPUS

80

초록

Robust induction of realistic angiogenesis into a 3D matrix material under simultaneous imaging and a stably controlled concentration gradient of chemoattractants is presented. The formation of a 3D vascular network is demonstrated to be a direct consequence of surface treatment of the region of the device-containing matrix material.

키워드

ENDOTHELIAL GROWTH-FACTOR; ANGIOGENESIS IN-VITRO; CELL-MIGRATION; COLLAGEN MATRICES; CULTURE; 3D; HYDROGEL; DEVICE; EXPRESSION; ENVIRONMENTS

제목: Surface-Treatment-Induced Three-Dimensional Capillary Morphogenesis in a Microfluidic Platform

저자: Chung, Seok; Sudo, Ryo; Zervantonakis, Ioannis K.; Rimchala, Tharathorn; Kamm, Roger D.

DOI: 10.1002/adma.200901727

발행일: 2009-12-18

유형: Article

저널명: Advanced Materials

권: 21

호: 47

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