Vascular characterization of clear cell sarcoma of the kidney in a child: a case report and review

초록

Clear cell sarcoma of the kidney (CCSK) is uncommon pediatric renal tumor and can present a significant therapeutic challenge in those patients whose tumors spread beyond the kidney. Thus, identifying potential novel targets for treatment may be clinically important. Clear cell sarcoma of the kidney is characterized by a unique vascular pattern, in which nests of turner cells are separated by regularly-spaced, fine fibrovascular septa. This distinctive histopathology raises the possibility that understanding the factors which drive angiogenesis in CCSK turners may suggest new therapeutic targets. Here, we describe a case of CCSK and present immunohistochemical studies of its vasculature. (C) 2009 Elsevier Inc. All rights reserved.

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