A Highly Crystalline Manganese-Doped Iron Oxide Nanocontainer with Predesigned Void Volume and Shape for Theranostic Applications

Vu Ngoc Phan; Lim, Eun-Kyung; Kim, Taekhoon; Kim, Minsik; Choi, Yuna; Kim, Byeongyoon; Lee, Myounghoon; Oh, Aram; Jin, Juhong; Chae, Youngjoo; Baik, Hionsuck; Suh, Jin-Suck; Haam, Seungjoo; Huh, Yong-Min; Lee, Kwangyeol

doi:10.1002/adma.201300525

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A Highly Crystalline Manganese-Doped Iron Oxide Nanocontainer with Predesigned Void Volume and Shape for Theranostic Applications

Vu Ngoc Phan;
Lim, Eun-Kyung;
Kim, Taekhoon;
Kim, Minsik;
Choi, Yuna;
... Lee, Kwangyeol;
외 9명

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31

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32

초록

Hollow Mn-doped iron oxide nanocontainers, formed by a novel one-pot synthetic process, fulfill the dual requirements of delivering an effective dose of an anticancer drug to tumor tissue and enabling image-contrast monitoring of the nanocontainer fate through T-2-weighted magnetic resonance imaging, thereby determining the optimal balance between diagnostic and therapeutic moieties in an all-in-one theranostic nanoplatform.

키워드

anisotropic etching; hydrophobic cavities; nanocontainers; magnetic resonance imaging; theranostics; DRUG-DELIVERY; MAGNETIC NANOPARTICLES; POTENTIAL PLATFORM; CONTROLLED-RELEASE; TARGETED DELIVERY; GOLD NANOCAGES; HOLLOW SPHERES; BREAST-CANCER; CHEMOTHERAPY; THERAPY

제목: A Highly Crystalline Manganese-Doped Iron Oxide Nanocontainer with Predesigned Void Volume and Shape for Theranostic Applications

저자: Vu Ngoc Phan; Lim, Eun-Kyung; Kim, Taekhoon; Kim, Minsik; Choi, Yuna; Kim, Byeongyoon; Lee, Myounghoon; Oh, Aram; Jin, Juhong; Chae, Youngjoo; Baik, Hionsuck; Suh, Jin-Suck; Haam, Seungjoo; Huh, Yong-Min; Lee, Kwangyeol

DOI: 10.1002/adma.201300525

발행일: 2013-06-18

유형: Article

저널명: Advanced Materials

권: 25

호: 23

페이지: 3202 ~ 3208

언어: ENG

출판사: WILEY-V C H VERLAG GMBH

발행국가: 독일

분량: 7 페이지

ISSN: E 1521-4095
P 0935-9648