A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells

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초록

We report a new Schiff base fluorescent probe which senses ferric ion, Fe(III), with a significant fluorescence enhancement response. The probe showed high sensitivity (0.8 ppb), and fast response time (<10 s) of Fe(III) in aqueous media. In addition, the probe showed the ability to sense Fe(III) in a HeLa cancer cell line, with very low cytotoxicity. As a new bio-imaging probe for Fe(III), it gave bright fluorescent images in confocal laser scanning microscopy (CLSM).

키워드

fluorescent probe; Schiff base probe; iron ion sensing; D-A type fluorophore; bioimaging; IRON; PROGRESS
제목
A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells
저자
Kim, Na Hee; Lee, Junho; Park, Sungnam; Jung, Junyang; Kim, Dokyoung
DOI
10.3390/s19112500
발행일
2019-06-01
유형
Article
저널명
Sensors
권
19
호
11