Age of menarche and near adult height after long-term gonadotropin-releasing hormone agonist treatment in girls with central precocious pubertyAge of menarche and near adult height after long-term gonadotropin-releasing hormone agonist treatment in girls with central precocious puberty
- Other Titles
- Age of menarche and near adult height after long-term gonadotropin-releasing hormone agonist treatment in girls with central precocious puberty
- Authors
- 백준우; 남효경; 진다희; 오연정; 이영준; 이기형
- Issue Date
- 2014
- Publisher
- 대한소아내분비학회
- Keywords
- Gonadotropin-releasing hormone; Precocious puberty; Central; Menarche
- Citation
- Annals of Pediatirc Endocrinology & Metabolism, v.19, no.1, pp.27 - 31
- Indexed
- KCI
- Journal Title
- Annals of Pediatirc Endocrinology & Metabolism
- Volume
- 19
- Number
- 1
- Start Page
- 27
- End Page
- 31
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/100321
- ISSN
- 1226-2242
- Abstract
- Purpose: Gonadotropin-releasing hormone agonist (GnRHa) is known for improvingfinal adult height in patients with central precocious puberty (CPP). This studyaimed to investigate the age of menarche and near adult height in girls with CPPwho had been treated with GnRHa.
Methods: In this retrospective study, we reviewed the medical records of 71 Koreangirls with CPP who had started menarche or reached over 13 years of bone ageafter long-term GnRHa treatment. We estimated near adult height using the Bayley-Pinneau method and identified the age of menarche in girls with CPP.
Results: Mean chronological and bone age at menarche were 11.9±0.7 and 12.8±0.4years, respectively. The period between menarche and the end of treatment was14.0±5.6 months. Posttreatment near adult height was 163.8±4.7 cm, which wassignificantly greater than pretreatment predicted adult height (158.7±4.1 cm).
Conclusion: GnRHa treatment in girls with CPP could improve final adult height andmade the age of menarche close to that of the general population.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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