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Real-time detection of trace copper in brain and kidney of fish for medical diagnosis
- Authors
- Yang, Y.K.; Pack, E.C.; Lee, S.H.; Yoo, H.-S.; Choi, D.W.; Ly, S.Y.
- Issue Date
- 2014
- Publisher
- Korean Society of Toxicology
- Keywords
- Brain cells; Copper; Fish; Kidney; Paste electrode
- Citation
- Toxicological Research, v.30, no.4, pp.311 - 316
- Indexed
- SCOPUS
KCI
- Journal Title
- Toxicological Research
- Volume
- 30
- Number
- 4
- Start Page
- 311
- End Page
- 316
- ISSN
- 1976-8257
- Abstract
- For the detection of trace copper to be used in medical diagnosis, a sensitive handmade carbon nanotube paste electrode (PE) was developed using voltammetry. Analytical optimized conditions were found at 0.05 V anodic peak current. In the same conditions, various common electrodes were compared using stripping voltammetry, and the PE was found to be more sharply sensitive than other common electrodes. At optimum conditions, the working ranges of 3~19 μgL-1 were obtained. The relative standard deviation of 70.0 μgL-1 was determined to be 0.117% (n = 15), and the detection limit (S/N) was found to be 0.6 μgL-1 (9.4 × 10-9 M). The results were applied in detecting copper traces in the kidney and the brain cells of fish.
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