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An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

Authors
Kwon, Young SeopRaston, Nurul Hanun AhmadGu, Man Bock
Issue Date
2014
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.50, no.1, pp.40 - 42
Indexed
SCIE
SCOPUS
Journal Title
CHEMICAL COMMUNICATIONS
Volume
50
Number
1
Start Page
40
End Page
42
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/101006
DOI
10.1039/c3cc47108j
ISSN
1359-7345
Abstract
A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.
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