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Organelle-selective fluorescent Cu2+ ion probes: revealing the endoplasmic reticulum as a reservoir for Cu-overloading

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dc.contributor.authorLee, Yun Hak-
dc.contributor.authorPark, Nayoung-
dc.contributor.authorPark, Young Bin-
dc.contributor.authorHwang, Yu Jeong-
dc.contributor.authorKang, Chulhun-
dc.contributor.authorKim, Jong Seung-
dc.date.accessioned2021-09-05T16:59:10Z-
dc.date.available2021-09-05T16:59:10Z-
dc.date.created2021-06-15-
dc.date.issued2014-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/101038-
dc.description.abstractTwo novel Cu2+ sensors, 1 and 2, bearing naphthalimide and a DPA moiety were synthesized to study copper accumulation in organelles by selective Cu2+ sensing. The ER-selective Cu2+ sensor 1 that we developed serves as a valuable tool for understanding the subcellular compartmentalization and roles of copper ions in physiology and pathophysiology.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectHUMAN CANCER-CELLS-
dc.subjectWILSONS-DISEASE-
dc.subjectMETAL-ION-
dc.subjectIN-VIVO-
dc.subjectCOPPER-
dc.subjectSENSOR-
dc.subjectBINDING-
dc.subjectEMISSION-
dc.subjectDESIGN-
dc.subjectCU(II)-
dc.titleOrganelle-selective fluorescent Cu2+ ion probes: revealing the endoplasmic reticulum as a reservoir for Cu-overloading-
dc.typeArticle-
dc.contributor.affiliatedAuthorKim, Jong Seung-
dc.identifier.doi10.1039/c4cc00091a-
dc.identifier.scopusid2-s2.0-84896884935-
dc.identifier.wosid000332115400018-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.50, no.24, pp.3197 - 3200-
dc.relation.isPartOfCHEMICAL COMMUNICATIONS-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume50-
dc.citation.number24-
dc.citation.startPage3197-
dc.citation.endPage3200-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusHUMAN CANCER-CELLS-
dc.subject.keywordPlusWILSONS-DISEASE-
dc.subject.keywordPlusMETAL-ION-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusCOPPER-
dc.subject.keywordPlusSENSOR-
dc.subject.keywordPlusBINDING-
dc.subject.keywordPlusEMISSION-
dc.subject.keywordPlusDESIGN-
dc.subject.keywordPlusCU(II)-
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