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Signal amplification by a self-assembled biosensor system designed on the principle of dockerin-cohesin interactions in a cellulosome complex

Authors
Hyeon, Jeong EunKang, Dae HeeHan, Sung Ok
Issue Date
2014
Publisher
ROYAL SOC CHEMISTRY
Citation
ANALYST, v.139, no.19, pp.4790 - 4793
Indexed
SCIE
SCOPUS
Journal Title
ANALYST
Volume
139
Number
19
Start Page
4790
End Page
4793
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/101062
DOI
10.1039/c4an00856a
ISSN
0003-2654
Abstract
To construct a self-assembled biosensor with signal amplification, a cellulosome system, comprising type I and type II dockerin-cohesin interactions with different specificities, from the anaerobic Clostridia bacterium was applied. The self-assembled biosensor was highly sensitive and achieved 128.1-fold increase in detection levels compared to the control.
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