Comparison of clinical outcomes between first-generation and second-generation drug-eluting stents in type 2 diabetic patients
DC Field | Value | Language |
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dc.contributor.author | Jeong, Han Saem | - |
dc.contributor.author | Cho, Jae Young | - |
dc.contributor.author | Kim, Eun Ji | - |
dc.contributor.author | Yu, Cheol Woong | - |
dc.contributor.author | Ahn, Chul-Min | - |
dc.contributor.author | Park, Jae Hyoung | - |
dc.contributor.author | Hong, Soon Jun | - |
dc.contributor.author | Lim, Do-Sun | - |
dc.date.accessioned | 2021-09-05T18:17:11Z | - |
dc.date.available | 2021-09-05T18:17:11Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2013-12 | - |
dc.identifier.issn | 0954-6928 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/101402 | - |
dc.description.abstract | BackgroundDrug-eluting stent (DES) implantation has significantly reduced the risk of restenosis and major adverse cardiac event (MACE) rates compared with bare-metal stents in type 2 diabetic patients. Differences in outcomes between the first-generation and second-generation DESs in diabetic patients, however, have yet to be evaluated.AimWe compared MACEs after second-generation DES implantation compared with those of first-generation stents in diabetic patients.Methods and resultsThis single-center prospective cohort study compared first-generation DES (n=654) and second-generation DES (n=339) implantation in type 2 diabetic patients by propensity score matching. The primary outcome was the occurrence of MACEs, defined as a composite of all-cause death, nonfatal myocardial infarction, and target vessel revascularization. The rate of MACEs was lower in the second-generation DES group after 2 years of follow-up (3.3 vs. 10.0%, P<0.001). Kaplan-Meier analysis showed higher MACE-free survival in diabetic patients in the second-generation DES group (log-rank P<0.001). In a Cox regression analysis, first-generation DES (hazard ratio=3.60, 95% confidence interval, 2.03-6.37, P<0.001) was an independent predictor for MACEs.ConclusionIn type 2 diabetic patients, second-generation DES implantation resulted in lower MACEs compared with first-generation DESs, primarily because of lower target lesion and vessel revascularization rates. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | BARE-METAL STENTS | - |
dc.subject | ANGIOGRAPHIC OUTCOMES | - |
dc.subject | CORONARY | - |
dc.subject | EFFICACY | - |
dc.subject | MELLITUS | - |
dc.subject | IV | - |
dc.subject | ANGIOPLASTY | - |
dc.subject | PREDICTORS | - |
dc.subject | RESTENOSIS | - |
dc.subject | DISEASE | - |
dc.title | Comparison of clinical outcomes between first-generation and second-generation drug-eluting stents in type 2 diabetic patients | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Hong, Soon Jun | - |
dc.contributor.affiliatedAuthor | Lim, Do-Sun | - |
dc.identifier.doi | 10.1097/MCA.0b013e3283650210 | - |
dc.identifier.scopusid | 2-s2.0-84888134819 | - |
dc.identifier.wosid | 000326972000009 | - |
dc.identifier.bibliographicCitation | CORONARY ARTERY DISEASE, v.24, no.8, pp.676 - 683 | - |
dc.relation.isPartOf | CORONARY ARTERY DISEASE | - |
dc.citation.title | CORONARY ARTERY DISEASE | - |
dc.citation.volume | 24 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 676 | - |
dc.citation.endPage | 683 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | BARE-METAL STENTS | - |
dc.subject.keywordPlus | ANGIOGRAPHIC OUTCOMES | - |
dc.subject.keywordPlus | CORONARY | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | MELLITUS | - |
dc.subject.keywordPlus | IV | - |
dc.subject.keywordPlus | ANGIOPLASTY | - |
dc.subject.keywordPlus | PREDICTORS | - |
dc.subject.keywordPlus | RESTENOSIS | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordAuthor | diabetes | - |
dc.subject.keywordAuthor | drug-eluting stents | - |
dc.subject.keywordAuthor | major adverse cardiac event | - |
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