Sex Differences in Hippocampal Neuronal Sensitization by Nicotine in M-gerbils
DC Field | Value | Language |
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dc.contributor.author | Hur, Young-Na | - |
dc.contributor.author | Lee, Joon | - |
dc.contributor.author | Sohn, Seung-Chan | - |
dc.contributor.author | Won, Chung-Gil | - |
dc.contributor.author | Lee, Hyung-Ha | - |
dc.contributor.author | Kim, Dong-Hoon | - |
dc.contributor.author | Choi, Sang-Hyun | - |
dc.contributor.author | Shin, Kyung-Ho | - |
dc.contributor.author | Chun, Boe-Gwun | - |
dc.date.accessioned | 2021-09-05T20:47:40Z | - |
dc.date.available | 2021-09-05T20:47:40Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2013-10 | - |
dc.identifier.issn | 1226-4512 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/102047 | - |
dc.description.abstract | We studied the sex different nicotine effect on evoked population spike amplitudes (ePSA) and connexin (Cx) expression in the hippocampus CA1 area of gerbils. Acute doses of nicotine bitartrate (0.5 mg/kg: NT-0.5) slightly reduced ePSA in males but markedly augmented that in females. Acute NT (5.0 mg/kg) markedly increased the ePSA in all gerbils. Unlike acute NT-0.5, repeated NT-0.5 injection (twice a day for 7 days) significantly increased the ePSA in males and slightly affected the NT-0.5 effect in females. The Cx36 and Cx43 expression levels as well as Cx expressing neuronal populations were significantly increased by repeated NT-0.5 in in both male and female gerbils, and particularly, Cx43 expression was somewhat prominent in females. These results demonstrated a sex difference with respect to the nicotine effect on hippocampal bisynaptic excitability, irrelevant to connexin expression. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY | - |
dc.subject | LONG-TERM POTENTIATION | - |
dc.subject | GAP-JUNCTIONS | - |
dc.subject | IN-VIVO | - |
dc.subject | MALE RATS | - |
dc.subject | EXPRESSION | - |
dc.subject | CA1 | - |
dc.subject | CELLS | - |
dc.subject | PLASTICITY | - |
dc.subject | RECEPTORS | - |
dc.subject | SUBFIELD | - |
dc.title | Sex Differences in Hippocampal Neuronal Sensitization by Nicotine in M-gerbils | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Dong-Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Sang-Hyun | - |
dc.contributor.affiliatedAuthor | Shin, Kyung-Ho | - |
dc.contributor.affiliatedAuthor | Chun, Boe-Gwun | - |
dc.identifier.doi | 10.4196/kjpp.2013.17.5.405 | - |
dc.identifier.scopusid | 2-s2.0-84888580360 | - |
dc.identifier.wosid | 000331593200004 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, v.17, no.5, pp.405 - 409 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY | - |
dc.citation.title | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY | - |
dc.citation.volume | 17 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 405 | - |
dc.citation.endPage | 409 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001816598 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Physiology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Physiology | - |
dc.subject.keywordPlus | LONG-TERM POTENTIATION | - |
dc.subject.keywordPlus | GAP-JUNCTIONS | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | MALE RATS | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | CA1 | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | PLASTICITY | - |
dc.subject.keywordPlus | RECEPTORS | - |
dc.subject.keywordPlus | SUBFIELD | - |
dc.subject.keywordAuthor | Connexin | - |
dc.subject.keywordAuthor | Evoked population spike | - |
dc.subject.keywordAuthor | Hippocampus | - |
dc.subject.keywordAuthor | Nicotine | - |
dc.subject.keywordAuthor | Sex difference | - |
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