Association between functional Fc receptor-like 3 (FCRL3)-169 C/T polymorphism and susceptibility to seropositive rheumatoid arthritis in Asians: A meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Song, Gwan Gyu | - |
dc.contributor.author | Bae, Sang-Cheol | - |
dc.contributor.author | Kim, Jae-Hoon | - |
dc.contributor.author | Kim, Young Ho | - |
dc.contributor.author | Choi, Sung Jae | - |
dc.contributor.author | Ji, Jong Dae | - |
dc.contributor.author | Lee, Young Ho | - |
dc.date.accessioned | 2021-09-05T22:05:04Z | - |
dc.date.available | 2021-09-05T22:05:04Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-09 | - |
dc.identifier.issn | 0198-8859 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/102258 | - |
dc.description.abstract | Objective: The aim of this study was to determine whether the functional Fc receptor like-3 (FCRL3) -169 C/T polymorphism confers susceptibility to rheumatoid arthritis (RA). Methods: A meta-analysis was conducted on the associations between the FCRL3 169 C/T polymorphism and RA. Results: A total of 17 comparison studies including 11,170 patients and 11,142 controls were considered in the meta-analysis. The meta-analysis showed no association between RA and the FCRL3 169 C allele in study subjects (OR = 1.046, 95% CI = 0.997-1.098, p = 0.068). Stratification by ethnicity indicated an association between the FCRL3 169 C allele and RA in Asians (OR = 1.101, 95% CI = 1.035-1.174, p = 0.002), but not in Europeans. Stratification of patients according to the presence of rheumatoid factor (RF) revealed a different significant association between the C allele and RA in RF-positive and RF-negative RA patients. Stratification by ethnicity indicated an association between the FCRL3 -169 C allele and RF-positive RA in Asians (OR = 1.093, 95% CI = 1.004-1.189, p = 0.040), but not in Europeans. Conclusions: This meta-analysis demonstrates that the FCRL3 169 C/T polymorphism may confer susceptibility to seropositive RA in Asians. (C) 2013 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | SYSTEMIC-LUPUS-ERYTHEMATOSUS | - |
dc.subject | GENE POLYMORPHISMS | - |
dc.subject | FCRL3 GENE | - |
dc.subject | POPULATION | - |
dc.subject | CAUCASIANS | - |
dc.subject | FAMILY | - |
dc.title | Association between functional Fc receptor-like 3 (FCRL3)-169 C/T polymorphism and susceptibility to seropositive rheumatoid arthritis in Asians: A meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Gwan Gyu | - |
dc.contributor.affiliatedAuthor | Kim, Jae-Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Sung Jae | - |
dc.contributor.affiliatedAuthor | Lee, Young Ho | - |
dc.identifier.doi | 10.1016/j.humimm.2013.05.018 | - |
dc.identifier.scopusid | 2-s2.0-84880952649 | - |
dc.identifier.wosid | 000322939400023 | - |
dc.identifier.bibliographicCitation | HUMAN IMMUNOLOGY, v.74, no.9, pp.1206 - 1213 | - |
dc.relation.isPartOf | HUMAN IMMUNOLOGY | - |
dc.citation.title | HUMAN IMMUNOLOGY | - |
dc.citation.volume | 74 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1206 | - |
dc.citation.endPage | 1213 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | SYSTEMIC-LUPUS-ERYTHEMATOSUS | - |
dc.subject.keywordPlus | GENE POLYMORPHISMS | - |
dc.subject.keywordPlus | FCRL3 GENE | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | CAUCASIANS | - |
dc.subject.keywordPlus | FAMILY | - |
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