Higher mortality in metabolically obese normal-weight people than in metabolically healthy obese subjects in elderly Koreans
DC Field | Value | Language |
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dc.contributor.author | Choi, Kyung Mook | - |
dc.contributor.author | Cho, Hyun Joo | - |
dc.contributor.author | Choi, Hae Yoon | - |
dc.contributor.author | Yang, Sae Jeong | - |
dc.contributor.author | Yoo, Hye Jin | - |
dc.contributor.author | Seo, Ji A. | - |
dc.contributor.author | Kim, Sin Gon | - |
dc.contributor.author | Baik, Sei Hyun | - |
dc.contributor.author | Choi, Dong Seop | - |
dc.contributor.author | Kim, Nan Hee | - |
dc.date.accessioned | 2021-09-05T22:18:02Z | - |
dc.date.available | 2021-09-05T22:18:02Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-09 | - |
dc.identifier.issn | 0300-0664 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/102337 | - |
dc.description.abstract | Objective The purpose of this study was to investigate the impact of body mass index (BMI) and the presence of metabolic syndrome (MetS) on all-cause and cardiovascular mortality in elderly Korean men and women, and especially to compare metabolically obese normal-weight (MONW) and metabolically healthy obese (MHO) subjects. Patients and methods A total of 2317 elderly people (over 60 years of age) were studied using follow-up data from the South-West Seoul (SWS) Study, a prospective cohort study. Mortality from all causes and cardiovascular disease (CVD) were evaluated according to the combination of the presence or absence of MetS and Asian-specific body mass index (BMI) criteria (BMI <23 kg/m(2); normal weight, BMI 23-24.9 kg/m(2); overweight, BMI >= 25 kg/m(2); obesity). Results During a median follow-up of 10.3 years, 393 subjects died, including 126 from CVD. Among subjects with MetS, all-cause and CVD mortality were significantly higher in normal-weight subjects than overweight or obese individuals in Cox proportional-hazard models adjusted for confounding factors. Furthermore, among six groups with various MetS/BMI combinations, MONW individuals had the highest risk, whereas overweight subjects without MetS had the lowest risk of death from all causes and CVD [HR = 2.2 (95% CI = 1.4-3.4), HR = 3.0 (95% CI = 1.4-6.6) respectively]. Interestingly, all-cause mortality was significantly higher in MONW than MHO individuals. Conclusions In contrast to MHO subjects, elderly individuals with the MONW phenotype exhibited greater all-cause mortality during 10 years of follow-up. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.subject | BODY-MASS INDEX | - |
dc.subject | SOUTH-WEST SEOUL | - |
dc.subject | CARDIOVASCULAR-DISEASE | - |
dc.subject | HEMODIALYSIS-PATIENTS | - |
dc.subject | INSULIN-RESISTANCE | - |
dc.subject | NATIONAL-HEALTH | - |
dc.subject | HEART-DISEASE | - |
dc.subject | ALL-CAUSE | - |
dc.subject | RISK | - |
dc.subject | MEN | - |
dc.title | Higher mortality in metabolically obese normal-weight people than in metabolically healthy obese subjects in elderly Koreans | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Kyung Mook | - |
dc.contributor.affiliatedAuthor | Seo, Ji A. | - |
dc.contributor.affiliatedAuthor | Kim, Sin Gon | - |
dc.contributor.affiliatedAuthor | Baik, Sei Hyun | - |
dc.contributor.affiliatedAuthor | Choi, Dong Seop | - |
dc.contributor.affiliatedAuthor | Kim, Nan Hee | - |
dc.identifier.doi | 10.1111/cen.12154 | - |
dc.identifier.scopusid | 2-s2.0-84880806753 | - |
dc.identifier.wosid | 000322186700012 | - |
dc.identifier.bibliographicCitation | CLINICAL ENDOCRINOLOGY, v.79, no.3, pp.364 - 370 | - |
dc.relation.isPartOf | CLINICAL ENDOCRINOLOGY | - |
dc.citation.title | CLINICAL ENDOCRINOLOGY | - |
dc.citation.volume | 79 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 364 | - |
dc.citation.endPage | 370 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | SOUTH-WEST SEOUL | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | HEMODIALYSIS-PATIENTS | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | NATIONAL-HEALTH | - |
dc.subject.keywordPlus | HEART-DISEASE | - |
dc.subject.keywordPlus | ALL-CAUSE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | MEN | - |
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