Selective and Efficient Deoxygenation of Sulfoxides with NbCl5/Indium System

Abstract

It has been found that dialkyl, diaryl, and aryl alkyl sulfoxides can be selectively converted to the corresponding sulfides with a NbCl5/In system in good to excellent yields under mild conditions. Several functional groups (bromo, chloro, methoxy, aldehyde, and vinyl) were tolerated under the reaction conditions. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.