Longitudinal Lung Volume Changes in Patients with Chronic Obstructive Pulmonary Disease
DC Field | Value | Language |
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dc.contributor.author | Lee, Jae Seung | - |
dc.contributor.author | Kim, Seon Ok | - |
dc.contributor.author | Seo, Joon Beom | - |
dc.contributor.author | Lee, Ji-Hyun | - |
dc.contributor.author | Kim, Eun Kyung | - |
dc.contributor.author | Kim, Tae-Hyung | - |
dc.contributor.author | Kim, Woo Jin | - |
dc.contributor.author | Lee, Jin Hwa | - |
dc.contributor.author | Lee, Sang-Min | - |
dc.contributor.author | Lee, Sangyeub | - |
dc.contributor.author | Lim, Seong Yong | - |
dc.contributor.author | Shin, Tae Rim | - |
dc.contributor.author | Yoon, Ho Il | - |
dc.contributor.author | Lee, Sei Won | - |
dc.contributor.author | Huh, Jin Won | - |
dc.contributor.author | Oh, Yeon-Mok | - |
dc.contributor.author | Lee, Sang-Do | - |
dc.date.accessioned | 2021-09-05T23:13:12Z | - |
dc.date.available | 2021-09-05T23:13:12Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-08 | - |
dc.identifier.issn | 0341-2040 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/102558 | - |
dc.description.abstract | The progression of lung hyperinflation in patients with chronic obstructive pulmonary disease (COPD) has not been studied in a long-term prospective cohort. We explored the longitudinal changes in lung volume compartments with the aim of identifying predictors of a rapid decline of the inspiratory capacity to total lung capacity ratio (IC/TLC). The study population comprised 324 patients with COPD who were recruited prospectively. Annual rates of changes in pulmonary function, including forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), total lung capacity (TLC), functional residual capacity (FRC), residual volume (RV), vital capacity (VC), IC, and IC/TLC, were estimated using the random coefficient models. The mean annual rates of changes in pre- and post-bronchodilator FEV1 were -23.0 mL/year (p < 0.001) and -26.5 mL/year (p = 0.004). The mean annual rates of changes in VC, IC, TLC, and IC/TLC were -33.7 mL/year (p = 0.007), -53.9 mL/year (p < 0.001), -43.7 mL/year (p = 0.012), and -0.65 %/year (p = 0.001), respectively. RV, FRC, and RV/TLC did not change significantly during the study period. Multivariate logistic regression analysis showed that a high modified Medical Research Council (MMRC) dyspnea scale score, a high Charlson comorbidity index value, and low post-bronchodilator FEV1 were associated with rapid decline in IC/TLC. MMRC dyspnea scale, post-bronchodilator FEV1, and the Charlson comorbidity index at baseline were independent predictors of a rapid decline in IC/TLC. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.subject | INSPIRATORY CAPACITY | - |
dc.subject | HYPERINFLATION | - |
dc.subject | EXERCISE | - |
dc.subject | IMPROVEMENT | - |
dc.subject | TIOTROPIUM | - |
dc.subject | HEALTH | - |
dc.title | Longitudinal Lung Volume Changes in Patients with Chronic Obstructive Pulmonary Disease | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Sangyeub | - |
dc.identifier.doi | 10.1007/s00408-013-9478-0 | - |
dc.identifier.scopusid | 2-s2.0-84880828247 | - |
dc.identifier.wosid | 000321916800013 | - |
dc.identifier.bibliographicCitation | LUNG, v.191, no.4, pp.405 - 412 | - |
dc.relation.isPartOf | LUNG | - |
dc.citation.title | LUNG | - |
dc.citation.volume | 191 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 405 | - |
dc.citation.endPage | 412 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | INSPIRATORY CAPACITY | - |
dc.subject.keywordPlus | HYPERINFLATION | - |
dc.subject.keywordPlus | EXERCISE | - |
dc.subject.keywordPlus | IMPROVEMENT | - |
dc.subject.keywordPlus | TIOTROPIUM | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordAuthor | Chronic obstructive pulmonary disease | - |
dc.subject.keywordAuthor | Spirometry | - |
dc.subject.keywordAuthor | Lung volume measurements | - |
dc.subject.keywordAuthor | Inspiratory capacity | - |
dc.subject.keywordAuthor | Total lung capacity | - |
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