Nano-Calcium Ameliorates Ovariectomy-Induced Bone Loss in Female Rats
DC Field | Value | Language |
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dc.contributor.author | Choi, Hyeon-Son | - |
dc.contributor.author | Han, JeungHi | - |
dc.contributor.author | Chung, Seungsik | - |
dc.contributor.author | Hong, Yang Hee | - |
dc.contributor.author | Suh, Hyung Joo | - |
dc.date.accessioned | 2021-09-05T23:14:47Z | - |
dc.date.available | 2021-09-05T23:14:47Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-08 | - |
dc.identifier.issn | 1225-8563 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/102568 | - |
dc.description.abstract | In this study, we examined the effects of organic types of calcium derived from oyster shell (OS-Ca) and nano-calcium (Nano-Ca) on the bio-availability and physiological responses associated with bone health in ovariectomised rats. Increased body weight, which is one of the physiological effects of ovary removal, was significantly recovered by Nano-Ca treatment (p<0.05). The reduced calcium level in the liver in ovariectomised rat was increased significantly with OS-Ca and Nano-Ca treatment (p<0.05), suggesting improved calcium bio-availability. Alkaline phosphatase (ALP), osteocalcin, and deoxypyridinoline (DPD) were analysed as biochemical markers of bone metabolism and health in the presence or absence of OS-Ca and Nano-Ca. ALP, osteocalcin, and DPD levels increased following ovary removal and tended to decrease after treatment with Nano-Ca, indicating that Nano-Ca induces favourable bone metabolism. This result was reflected in the recovery of bone mineral density (BMD) and bone mineral content (BMC) of the femur after Nano-Ca treatment following ovary removal. Taken together, our data show that the tested calcium treatments, especially using Nano-Ca, enhanced the bio-availability or absorption of calcium and positively affected bone metabolism in ovariectomised rats. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC FOOD SCIENCE ANIMAL RESOURCES | - |
dc.subject | SUPPLEMENTATION | - |
dc.subject | RESORPTION | - |
dc.subject | PHYTOESTROGEN | - |
dc.title | Nano-Calcium Ameliorates Ovariectomy-Induced Bone Loss in Female Rats | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Suh, Hyung Joo | - |
dc.identifier.doi | 10.5851/kosfa.2013.33.4.515 | - |
dc.identifier.scopusid | 2-s2.0-84894209958 | - |
dc.identifier.wosid | 000335122700012 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES, v.33, no.4, pp.515 - 521 | - |
dc.relation.isPartOf | KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES | - |
dc.citation.title | KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES | - |
dc.citation.volume | 33 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 515 | - |
dc.citation.endPage | 521 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001798703 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | SUPPLEMENTATION | - |
dc.subject.keywordPlus | RESORPTION | - |
dc.subject.keywordPlus | PHYTOESTROGEN | - |
dc.subject.keywordAuthor | ovariectomy | - |
dc.subject.keywordAuthor | nano-calcium | - |
dc.subject.keywordAuthor | calcium bioavailability | - |
dc.subject.keywordAuthor | bone metabolism | - |
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